If not treated, MTHFR mutations can cause a buildup of folic acid and make mood and behavioral disorders worse, and treatment of them more difficult (especially mood disorders).

The build up of folic acid may be the reason why some kids with ADHD have sensitivities or rare reactions to medications, and even supplements. It also explains why mood and behavior can worsen when your child takes a regular multivitamin, or even eats fortified cereals.

Symptoms of MTHFR mutation vary among individuals and depending on the type of mutation. Some people may have no symptoms at all, others may have more serious complications like increased risk for heart disease, sluggish detox, miscarriages, and more. People usually do not know that they have an MTHFR mutation unless they experience severe symptoms or undergo genetic testing.

Children with MTHFR gene mutation may be at increased risk for ADHD, learning disabilities, autism, or autoimmune disorders. However, just because one inherits the mutation, it does not necessarily mean they will have the problem.

Having one or two MTHFR mutations can slightly increase the levels of homocysteine present in the blood. Homocysteine is an amino acid that the body produces by breaking down dietary proteins.

High levels of homocysteine can damage blood vessels and lead to blood clots. People who have high homocysteine levels tend to have low levels of vitamin B12.

Symptoms of homocystinemia due to MTHFR mutations include:

• abnormal blood clotting
• developmental delays
• seizures
• microcephaly
• poor coordination
• numbness or tingling in the hands and feet

First of all, avoid extra folic acid, the synthetic form of folate. People who have MTHFR gene defect cannot use folic acid properly and often don’t feel well after taking it.

Many B vitamin supplements, multivitamins, energy drinks, protein bars, and processed foods contain synthetic folic acid, and therefore, should be avoided.

Avoid the synthetic version of B12 (cyanocobalamin) and instead use the bioactive forms (methylcobalamin, hydroxycobalamin and adenosylcobalamin). Avoid exposure to environmental toxins and eat a clean diet wherever possible as detoxification process is slowed with MTHFR defect.

There are other forms of folate that are generally better for those with MTHFR including 5-MTHF, methylfolate, and folinic acid.

Of course, you can always get the natural folate from naturally folate-rich foods including spinach, asparagus, chickpeas, beans, broccoli, and dark green leafy vegetables. These foods naturally contain a form of folate that is more bioavailable and generally easier for the body to make use of.

Methylated versions of supplements like folate (methylfolate) and B-12 (Methylcobalamin, hydroxycobalamin, or adenosylcobalamin) are often recommended, as well as the biologically active form of B6 (pyridoxal-5-phosphate or P-5-P).

PureGenomics B-Complex by Pure Encapsulation is designed specifically to address the nutrient requirements of common genetic variations in the methylation pathway with a unique blend of bioactive B vitamins. 

Ok, there you have it…

I hope you find this information helpful. Let me know what you think and comment below. 

Remember ADHD does not doom your child to a life of under-achievement. You know your child is bright, full of potential, and deserves the best. In fact, many of the world’s greatest discoveries and inventions were made by people with ADHD.

If you’re just starting out on this natural ADHD treatment journey and still in the research phase, check out my new book Eat to Focus. Inside this book, you’ll learn why your ADHD child is always hungry, why he or she seems addicted to milk and bread, the underlying causes of ADHD, and the most effective ADHD treatment that addresses all the causes to reduce hyperactivity, impulsiveness, and anxiety while improving focus and calmness in your ADHD child. 

Don’t forget to download your free gift 15 Quick & Simple ADHD-Friendly Breakfast Ideas before you leave.