Heal Your Leaky Gut

Journey to a Happy Healthy Gut

Now that we have more understanding of what leaky gut is and what the causes are, let’s explore the journey to healing.

Notice that I use the word “journey”…meaning healing is a process and will take time.

Remember the vicious cycle of leaky gut did not happen overnight and so is the healing process.

Are you ready for a change for the better?

Here are the critical steps toward a healthy and happy gut.

We know the gut is very delicate and sensitive, and so the first order of business is to stop putting toxin in your body.

Translation: Change your diet.

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As Michael Pollan eloquently states “Eat Food. Not Too Much. Mostly Plants” in his book “Omnivore Dilemma”.

Researches, studies, multiple counts of experiences point toward the beneficial effects of an anti-inflammatory plant-based diet.

I recommend eating an plant-based diet that is rich in essential fatty acids, such as omega-3 fatty acids and gamma linolenic acid GLA, and insoluble fiber.

Many naturally occurring substances from plant-based foods help repair the intestinal mucosal surface or support the liver when stressed by enteric toxins.

Essential fatty acids (EFAs) are the substrates for prostaglandin synthesis. Fish oil has been shown to resolve intestinal mucosal injury and stops the systemic response to endotoxin. Gamma-linolenic acid (GLA) promotes the synthesis of E-series prostaglandins, which decrease permeability.

Our body can make GLA from linoleic acid via an enzymatic reaction catalyzed by deta-desaturase (D6D). However, this reaction is limiting and consumption of excessive vegetable oils may increase the free radical content of bile and exacerbates the effects of endotoxin.

EFAs should be consumed in the most concentrated and physiologically active form to avoid exposure to large quantities of polyunsaturated fatty acids from dietary oils.

Good dietary sources of GLA are evening primrose oil, black currant seed oil, hemp seed oil and borage oil.

Insoluble fiber has been shown to decrease permeability. So eat a diet rich in insoluble fiber or supplement with pure cellulose or rice bran. An added benefit of rice bran is gamma oryzanol. It is an antioxidant in rice bran that has healing effects in gastric and duodenal ulceration.

Soluble fiber, on the other hand, increases permeability, and should be consumed in limited amount.

Avoid any foods that you’re allergic and/or sensitive to as allergic reactions increase gut permeability. When taken before eating, Quercetin may help to stop the release of histamine and inflammatory mediators in an allergic reaction.

Chewing your food well may actually help to nourish your gut with salivary Epidermal Growth Factor (EGF). It is a polypeptide that stimulates growth and repair of epithelial tissue. It is found throughout your body, with high concentrations in salivary glands, prostate glands and in the duodenum.

Take a probiotics supplement containing Lactobacillus GG may help repopulate the good bacteria population that is the result of the leaky gut, and reverse bacterial dysbiosis.

In addition, supplementing your diet with glutamine can be beneficial. Glutamine is an important substrate for the maintenance of intestinal metabolism and integrity. Glutamine supplementation has been shown to reverse intestinal mucosal injury, resulting in less villous atrophy, increased mucosal healing and decreased passage of endotoxin through the gut wall.

Support your liver with glutathione (GSH), which is an important component of the anti-oxidant defense against free radical-induced tissue damage. Hepatic GSH is a key ingredient for reducing toxic oxygen metabolites and oxidized xenobiotics in the liver. When the liver is working overtime trying the get rid of the toxic waste in the leaky, the demand for glutathione is high because the liver is using it up very quickly.

The most effective way to increase glutathione level in liver is to supplement with its dietary precursors, cysteine or methionine, such as N-acetylcysteine. Flavonoids in milk thistle (silymarin) and in dandelion root (taraxacum) also help to support the liver by protecting against reactive oxygen species.

An additional step to support and nurture your liver is to let it rest, as in stop ingesting more toxins from processed foods, fast foods, food colorings, food additives, pesticides, preservatives, artificial sweeteners, medications, legal drugs, etc.

And of course avoid alcohol even if it’s red wine.

Sorry…I know it’s confusing. One says red wine is good for you and another says alcohol is bad for you. If you have a leaky gut, alcohol is definitely bad for you. So sober up, at least until your leaky gut is under control.

And did you know…you can get the same resveratrol from a supplement and minus the alcohol and save your liver.

NSAIDS are all your pain-killers. They are known to cause GI bleed. I know you need them to control your pain. Did you know most of your aches and pains are the result of systemic inflammation caused by all the toxins you put in your body?

That’s why I put this step last. Because when you start doing all the things listed above, your body is slowly healing itself and recovering, and the inflammation eventually stops and so will your aches and pain. And when that they comes, you’ll not need your pain killer anymore.

Bone broth is supposed to be good for leaky gut. A colleague buys “chicken feet” from Whole Foods and boils them with some vegetables for 24 hours in a slow cooker to get all the gelatin out of the bone. Just flavor with a little salt and you have a yummy broth for your tummy.

Relaxation helps lower stress hormone. Activities like yoga, meditation, walk in the nature, hiking, exercise, etc. These activities not only reduce your stress hormones, but they can also increase your feel good hormone – endorphins.

When you follow these steps, your gut will start feeling better, aches and pain will disappear, brain fog will clear up, and ADHD symptoms will improve.

Return to What You Need to Know About Leaky Gut





Immune-Boosting with N-Acetylcysteine (NAC)




Immune-boosting N-acetylcysteine

N-acetylcysteine (NAC) is naturally produced in our body from cysteine, a sulfur-containing amino acid. It is the acetylated form of L-cysteine. NAC is also the precursor to glutathione, a natural antioxidant and detoxifier that our body produces. N-acetylcysteine is more easily absorbed than either glutathione or L-cysteine.

HOW DOES IT WORK?

ADHD, autism and many other developmental disorders are thought to be the result of defective detox system and abnormal accumulation of toxic chemicals and heavy metals.

NAC acts as an antioxidant and a free radical-scavenging agent to support the body’s detox system. It protects the liver by preventing the abnormal accumulation of lipids within liver cells due to oxidative stress, and against environmental pollutants, such as carbon monoxide, chloroform, urethane, and certain herbicides and reduces the toxicity of ifosfamide and doxorubicin used in cancer treatment, and alcohol toxicity. NAC is used among other chelating agents to eliminate heavy toxic metals, such as mercury, lead, cadmium and arsenic from the body.

NAC or cysteine participates in the sulfation cycle of the body, acting as a sulfur-donor in phase II of the detoxification system, and methyl donor in the conversion of homocysteine to methionine. NAC has also been show to protect against neuronal death induced by oxidative stress.

OTHER BENEFITS OF NAC

NAC helps improve lung functions by breaking the disulfide bonds in mucoprotein molecules. This results in thinning of mucus in the lungs making it easier to cough up and clear out. This is especially helpful in people with chronic bronchitis, chronic obstructive pulmonary disease (COPD), hay fever, cystic fibrosis, fibrosing alveolitis, head and neck cancer, and lung cancer.

It also protects against heart diseases, such as heart attacks and strokes, in patients with severe kidney diseases by reducing the levels of cholesterol, lipoprotein-a, homocysteine. Remember? NAC helps to convert homocysteine into methionine.

NAC is used as an antidote for acetaminophen intoxication by binding to the acetaminophen in the liver, and then excreting it.

SUPPLEMENTATION


N-acetylcysteine is more easily absorbed by the body than either glutathione or L-cysteine. Purified glutathione supplement is not very well absorbed by the body.

Studies show that dosage of up to 40mg/kg of NAC in children is safe.

NAC increases excretion of zinc and other essential minerals. When taking NAC over a long period of time, it is wise to supplement diet with zinc, copper and trace minerals.

Get your high quality NAC here…




CoQ10 for ADHD




What is Co Q 10?
Coenzyme Q10 is a natural antioxidant synthesized by the body, found in many foods, and available as a supplement. It comes in two forms: ubiquinol, the active antioxidant form, and ubiquinone, the oxidized form, which the body partially converts to ubiquinol. It is also known as ubiquinone, ubidecarenone, coenzyme Q, and eventually it is abbreviated to CoQ10 , CoQ.

This fat-soluble, vitamin-like substance is present primarily in the mitochondria, the body’s power station. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way. It is found in every cell of the body. Those organs with the highest energy requirements—such as the heart, liver and kidney—have the highest CoQ10 concentrations.

How Does Co Q 10 Help?

Co Q 10 maybe beneficial for children with ADHD in that it helps with membrane stabilization and the facilitation of metabolic pathways.  Co Q 10’s main function is that of an energy carrier. It participates in the aerobic cellular respiration inside the mitochondria, generating energy in the form of ATP.

Co Q 10’s antioxidant property derives from its role as energy carrier. As an energy carrier, the CoQ10 molecule is continually going through an oxidation-reduction cycle, which gives Co Q 10 the ability to exchange two electrons between ubiquinol (reduced CoQ) and oxidized CoQ (ubiquinone). Its reduced form makes it an excellent candidate as an antioxidant by giving up one or two of its electrons to wandering free radicals, thus, neutralizing them.

Unlike other antioxidants, Co Q 10 protects the body against the resultant oxidative stress from both the lipid peroxidation and protein oxidation. It also regenerates other antioxidants such as vitamin E. It’s benefit in cardiovascular disease lies in its protection against oxidation of LDL (bad cholesterol). And during oxidative stress, as in most children with ADHD and Autism, or adults with Alzheimer’s disease, Co Q 10 efficiently prevents the oxidation of bases on the DNA, in particular, mitochondrial DNA.

When shopping for Co Q 10, you’ll notice that most are advertised for heart health. Co Q 10 is mostly marketed for heart health in the United States because heart disease is the number killer in the US, followed by cancer. Go figure $$$$$$$$$

However, the antioxidant function of Co Q 10 does not only benefit heart disease. It can benefit any diseases or conditions that are the result of excessive free radicals, oxidative stress, daily physical, emotional and psychological stress.

Co Q 10 also plays a critical role in enhancing the immune system as well. It has been shown that patients with cardiovascular problems, cancer, and diabetes, taking 60mg of Co Q 10 a day for 3-12 weeks, raised their levels of immunoglobulin G (IgG), an antibody, levels significantly. IgG protects the body again infection by binding many kinds of pathogens, such as viruses, bacteria, and fungi. Some research has suggested that this immune-enhancing function of CoQ10 maybe useful as a secondary treatment for cancer. In 1961, scientists saw that people with cancer had very low level of CoQ10 in their blood, especially patients with myeloma, lymphoma, and cancers of the breast, lung, prostate, pancreas, colon, kidney, and head and neck.

How Much Co Q 10 do We Need?

Our body has the ability to make Co Q 10. However, typical American diet provides only approximately 10 mg of CoQ10 daily. Not to mention, physical, mental and emotional stress, all forms of stress, illness and aging all contributes to the depletion of co Q 10 in the body, which increased body’s need of this substance even more than usual.

Therefore, supplementation is usually necessary to reach the amounts that Dr. Weil regards as optimal. Foods such as codfish, mackerel, salmon, sardines, egg yolks, wheat germ, whole grains, meats, and oils from soybean, sesame, and rapeseed (canola) are good dietary sources.

To get 30mg of Co Q 10, you needs to eat one pound of sardines, 2 pounds of beef, or two and a half pound of peanuts.

CoQ10 Food Sources

CoQ10 is fat-soluble, so taking the supplement with a meal containing fat will increase its absorption.

Co Q 10 supplements come in various forms. The gummies that generally more acceptable to children as it does not require any swallowing skill, it is familiar to most children as gummy candy, and it is generally quite tasty. Just remember not to leave the bottle around within reach of your child.

If your child is capable of swallowing pills, or prefer to swallow a pill, choose the soft-gel ubiquinol form, as this has greater antioxidant efficiency than the ubiquinone form.

Most supplements sold in the market are around 100-200mg per tablet, which is a pretty decent amount for most adult to start.

How much does a child need?

General rule of thumb for children over 2 years old is half of the adult dose. I suggest talking with your child’s pediatrician before starting him or her on CoQ10 supplementation. I understand that many doctors are still not quite supportive of any natural alternative treatment, but, talk to them anyway as a courtesy gesture and ask for their support.

How Much is Too Much?

There is not much evidence on the toxicity of CoQ10, but so far, evidence shows that supplemental doses of up to 1,200 mg a day may be beneficial for those with certain health conditions, especially Parkinson’s disease, with no known side-effects.

Some studies have found gastrointestinal discomfort was reported with high daily dosages of up to 3,600 mg.

These are really high doses that are usually seen in scientific research and signed consent form and human study agreement…blah, blah, blah. So don’t even try to get that much. Even half of these amounts are too much for most people.

Get Your CoQ10 Here